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eLife6d
Somatic hypermutation patterns in immunoglobulin variable regions are established independently of the local transcriptional landscape
Somatic hypermutation (SHM) of immunoglobulin variable (V) regions modulates antibody-antigen affinity is initiated by activation-induced cytidine deaminase (AID) on single-stranded DNA (ssDNA).
Nature5d
Continuous requirement for the TCR in regulatory T cell function
To investigate the role of TCR signaling in T reg cell function, we crossed Trac FL mice (which have a loxP-flanked allele encoding the TCR α-chain constant region (C α or TCRα)) with Foxp3 ...
ahajournals.org5d
VEGF (Vascular Endothelial Growth Factor) Functionalized Magnetic Beads in a Microfluidic Device to Improve the Angiogenic Balance in Preeclampsia
Tween 20 was from Sigma-Aldrich. Human recombinant sFlt-1 with an antibody constant fraction (rhVEGFR1/Fc Chimera, Ser27-His687) and human recombinant PlGF (rh PlGF) were from R&D Systems. Kits from R ...
C&EN6d
Injectable Hydrogels for Sustained Codelivery of Subunit Vaccines Enhance Humoral Immunity
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