The AlphaRED docking strategy demonstrates a new and better way to predict protein complex structures within feasible compute times. This work is particularly impactful for its success rate on ...

Nanobodies, tiny, single-domain antibody fragments derived from camels and sharks ... However, challenges persist, particularly in modeling kinked CDR3 loops and in antigen-docking accuracy—where ...

Researchers at the Ragon Institute have made a significant discovery about how antibodies can directly enhance the body's ...

Singapore's national platform for drug discovery and development, has announced the presentation of updated clinical data for ...

"Even in Hitler’s Germany, you could cross the Alps to Switzerland. You could hide in an attic like Anne Frank did." ...

We have developed a method that combines dynamic force microscopy with the simultaneous molecular recognition of an antigen by an antibody, during imaging. A magnetically oscillated atomic force ...

At active dose levels (≥ 50 µg/kg), 26 of 33 evaluable patients (79%) achieved objective responses, including stringent or ...

Antibodies are secreted immunoglobulin molecules produced mainly by plasma cells. The antigen-binding site of the antibody has a unique structure that allows it to bind antigen in a highly ...

3) Biolojic Design: Founded in 2009, the Israeli company uses a structure-based approach, where their model is trained on millions of Antibody-Antigen pairs in order to identify a template ...

COLUMBUS, Ohio – Scientists have engineered a monoclonal antibody that can protect mice from a lethal dose of influenza A, a new study shows. The new molecule combines the specificity of a ...

In recent years, the therapeutic landscape for hematological malignancies has undergone a profound transformation, driven by the development and regulatory ...

Annual Meeting held in Chicago, IL, was host to a State of the Science session on novel diagnostics and therapeutics in renal cell and urothelial carcinomas. Dr. Wulff-Burchfield discussed strategies ...