This repository contains the antibody-antigen test cases, with unbound and bound structures, for Docking Benchmark 5.5. This dataset is a major update of Docking Benchmark 5.0, which was released in ...

Antisperm Antibody. An ASA is defined as an immunoglobulin with antibody activity against a sperm antigen that plays a ... nucleoporin and possibly acts as a docking site and a ...

However, these serological assays have several drawbacks, such as the selection of viral antigens and human antibody isotypes, as well as errors, inaccuracy, cross-reactivity, interbatch variability, ...

Abs make up one of the most important classes of advanced biotherapies. GEN interviewed leaders about current challenges and ...

The potential of monoclonal antibodies (mAbs) as therapies is indisputable. The current mAbs market is expected to be around ~USD 150 billion. In 2021, five out of the top 10 selling drugs were ...

The well-studied NF-κB signaling system is a key mediator of the inflammatory response. Large-scale sequencing studies in ...

This huge antigen-binding variety, generated by somatic gene recombination and—in most cases—hypermutation of their antigen-binding variable regions, results in a unique set of antibodies in each ...

Conformational diversity and self-cross-reactivity of antigens have been correlated with evasion from neutralizing antibody responses. We utilized single cell B cell sequencing, biolayer ...

Gold nanoparticles (AuNPs) functionalized with antibodies have the potential to improve biosensing technology because of the unique optical properties of AuNPs and the specificity of antibody–antigen ...