Learn how antibody to payload design is crucial for advancing ADC technology in oncology and beyond with expert insights.

Researchers at the Ragon Institute have made a significant discovery about how antibodies can directly enhance the body's ...

We have developed a method that combines dynamic force microscopy with the simultaneous molecular recognition of an antigen by an antibody, during imaging. A magnetically oscillated atomic force ...

Find more information on the Altmetric Attention Score and how the score is calculated. Antibody orientation and its antigen binding efficiency at interface are of particular interest in many ...

Such reproductions, however, appear to be running into the same issues, indicating that global antibody-antigen docking/co-folding is still out of reach, and to get at reasonable models one needs to ...

This useful manuscript provides a newly curated database (termed AACDB) of antibody-antigens structural information, alongside annotations that are either taken and from the PDB, or added de-novo.

Methods to probe the antigen-specific B cell response have advanced our understanding ... vaccine candidates that elicit protective antibodies; (2) antibodies that prevent disease when given ...

Nanobodies, tiny, single-domain antibody fragments derived from camels and sharks ... However, challenges persist, particularly in modeling kinked CDR3 loops and in antigen-docking accuracy—where ...

The purpose of the present study was to evaluate the avidity of IgG antibodies against excreted/secreted antigens of Toxoplasma gondii by means of immunoblot, to establish a profile for acute recent ...

Antibodies are widely used biomarkers for the diagnosis of many diseases. Assays based on solid-phase immobilization of antigens comprise the majority of clinical platforms for antibody detection, but ...

This work introduces and describes a useful curation pipeline of antibody-antigen structures downloaded from the PDB database. The antibody-antigen structures are presented in a new database called ...