Current methods of antibody detection, such as conventional serological assays, are limited in terms of the amount of ...

B lymphocytes exhibit dual roles in tumorigenesis, acting as both allies and adversaries in the tumor microenvironment (TME).

B lymphocytes exhibit dual roles in tumorigenesis, acting as both allies and adversaries in the tumor microenvironment (TME).

Researchers show that analyzing the 3D shapes of antibodies, not just their genetic sequences, can better group functionally ...

We selected a streptavidin-coated 96-well plate to evaluate the antigen-binding capacity of the randomly and site-specifically biotinylated antibodies. This is a commercially available solid-phase ...

such as antigens or immunogens. That binding process depends on many factors. “One often overlooked parameter is the exact binding site of your antibody on the protein of interest, also known as ...

These are proteins that bind to specific antigens on target cells, such as bacteria. Monoclonal antibodies work similarly, binding only to specific antigens. This can help the body fight disease.

Each of these modified antibodies still maintained trastuzumab-specific binding to cells expressing the HER2 antigen, the target of trastuzumab ... that would allow release of the cargo at that site.

the C-terminal fusion of a pair of weakly homodimerizing proteins to three different antibodies enhanced the antigen-binding avidity by at least 110 or 304 folds from the intrinsic binding avidity.