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C&EN2d
Antitubercular Nucleosides That Inhibit Siderophore Biosynthesis: SAR of the Glycosyl Domain | Journal of Medicinal Chemistry - ACS Publications
Tuberculosis is the leading cause of infectious disease mortality in the world by a bacterial pathogen. We previously demonstrated that a bisubstrate inhibitor of the adenylation enzyme MbtA, which is ...
SciELO7d
Kinetic and equilibrium mechanisms of substrate binding to Mycobacterium tuberculosis enoyl reductase: implications to function-based antitubercular agent design - SciELO - Brasil
ARTICLE. Kinetic and equilibrium mechanisms of substrate binding to Mycobacterium tuberculosis enoyl reductase: implications to function-based antitubercular agent design. Igor B. Vasconcelos; Luiz A.
C&EN11d
Design, Synthesis, and Characterization of N-Oxide-Containing Heterocycles with in Vivo Sterilizing Antitubercular Activity | Journal of Medicinal Chemistry - ACS Publications
Tuberculosis, caused by Mycobacterium tuberculosis (Mtb), is the infectious disease responsible for the highest number of deaths worldwide. Herein, 22 new N-oxide-containing compounds were synthesized ...
Nature22d
New antituberculous drugs derived from natural products: current perspectives and issues in antituberculous drug development
Antitubercular activity of water-insoluble ilamycin. J. Antibiot. B 16, 93–98 (1963). CAS PubMed Google Scholar Gao, W. et al. The cyclic peptide Ecumicin ...