The profibrogenic response was dependent upon apoptotic body engulfment, because nocodazole, a microtubule-inhibiting agent, blocked both the engulfment and the increase of TGF-β1 and collagen ...

Actomyosin contraction provides the force-driving contraction, membrane blebbing and apoptotic body formation during programmed cell death. Apoptotic cells display cell surface markers that ...

The predominant signatures of apoptosis include the loss of cell volume, or cell shrinkage, nuclear condensation, internucleosomal DNA fragmentation, and apoptotic body formation. We examine the ...

“In May of this year we announced and filed a patent on the ApoptoCyte procedure which involves the induction of cellular suicide in the stem cell, extraction of small vesicles called ...

In this paper, the team separated the small apoptotic bodies (sABs) and revealed their potential advantages as a delivery system for brain targeting. First, compared with the micron-sized ...