Although Chinese hamster ovary (CHO) cells have dominated therapeutic protein expression systems for decades, biomanufacturers still must deal with their inconsistent expression levels and varying ...

Chinese hamster ovary (CHO) cells are the cornerstone of biopharmaceutical production, accounting for 70% of all approved recombinant protein production. These immortalized cells offer high ...

Scientists have developed a new strategy to enhance pharmaceutical production in Chinese hamster ovary (CHO) cells, which are commonly used to manufacture protein-based drugs for treating cancer ...

Matsunaga’s research team succeeded in transferring the chloroplasts by promoting phagocytosis by the CHO cells, which is the process by which cells digest and break down foreign substances.

Further, Alvotech’s SELARSDI (ustekinumab-aekn) and Amgen’s WEZLANA (ustekinumab-auub) are also manufactured using a Sp2/o host cell line or a glyco-engineered CHO cell-line system.

that along with bacteria and eukaryotic cells, archaea also exchange vesicle-bound RNA, which confirms that the phenomenon is universal to all three domains of life. Another study has expanded our ...

Solar cells that combine traditional silicon with cutting-edge perovskites could push the efficiency of solar panels to new heights. Beyond Silicon, Caelux, First Solar, Hanwha Q Cells ...

A key element of the RV144 trial was gp120, generated in Chinese Hamster Ovary (CHO) cells and deficient in N-linked glycosylation sites vital for binding several families of anti-HIV broadly ...

Research roadblocks and political debates have delayed progress—but scientists are inching closer to delivering a cure. Twenty-five years ago, in 1998, researchers in Wisconsin isolated ...

Archaea in a warming climate become less diverse, more predictable Date: May 5, 2023 Source: University of Oklahoma Summary: Using a long-term multifactor experimental field site researchers ...