Cancers resemble wounds. The question is why, and what does this mean? Many features of cancers – the so-called ‘Hallmarks of Cancer' ...

Collective cell migration is defined as the coordinated ... Simple 2D monolayers of cells move either constitutively across an intact basement membrane, such as the gut intestinal epithelium ...

Cell polarity is the asymmetric organisation ... Here, the authors show that Net1 mRNA targeting to the basement membrane controls epithelial tissue organization and keratinocyte-stromal connections.

Oesophageal adenocarcinoma has an extremely poor prognosis, and improving outcomes via therapy remains particularly challenging in such a heterogeneous cancer. Another avenue for improving outcomes ...

Neoantigen-specific tumor-infiltrating lymphocytes achieve precise tumor cell killing by recognizing neoantigens ... and abnormal connections between the basement membrane and pericytes. High IFP ...

Chinese scientists have developed a breakthrough process that significantly improves the efficiency and environmental ...

Scientists have discovered that the internal shape of tiny drug-delivery particles—called lipid nanoparticles—has a big ...

Kennedy researchers have uncovered key design parameters for bispecific T-cell engagers (TcEs)—a class of cancer ...

Mathieu Bennet: In B-cell cloning, single-cell isolation occurs at two crucial stages. First, during the initial screening phase, high-throughput isolation is required to analyze a broad antibody ...

Recessive dystrophic epidermolysis bullosa (RDEB) is a systemic disease of poor mucocutaneous basement membrane integrity downstream of bi-allelic pathogenic variants in COL7A1. Cutaneous clinical ...

Using QCM-D, the study tracks diffusion, aggregation, and incorporation of DNPs, highlighting the role of cholesterol anchors and substrate composition in membrane insertion—advancing ...