The research, published in Developmental Cell, is the first to show how local cells sense and respond to changes in basement membrane stiffness caused by damage—and how they activate a ...

Large gaps in basement membrane occur at sites of cell invasion and tissue remodelling in development and cancer. Though never followed directly in vivo, basement membrane dissolution or reduced ...

Immunohistochemical staining of basement membrane components, including laminin 1 (a), laminin 5 (b), collagen type IV (c) and fibronectin (d) in a granular cell ameloblastoma.

In addition, for the first time this study determined how long immune cells need to penetrate the basement membrane after crossing the endothelial cell layer. The researchers measured a time of 40 ...

The teams and their collaborators are now assessing how filopodia regulate basement membranes' assembly. Reference: Peuhu E, Jacquemet G, Scheele CLGJ, et al. MYO10-filopodia support basement ...

Basement membranes also play a signaling role, acting sort of like a cellular thermostat. “If the basement membrane misbehaves, then the cell misbehaves,” comments Raghu Kalluri, ...

Most tumors are sheathed in a protective "basement" membrane -- a thin, pliable film that holds cancer cells in place as they grow and divide. ... MIT, with cell images courtesy of the researchers.

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Breast cancer cells break through the basement membrane acting as a biological barrier. In the image, the finger-like projections formed by the actin of cancer cells invading the surrounding cell ...

All the latest science news on basement membrane from Phys.org. Find the latest news, advancements, and breakthroughs. Topics. ... Cell & Microbiology Jan 2, 2025 ...

image: Breast cancer cells break through the basement membrane acting as a biological barrier. In the image, the finger-like projections formed by the actin of cancer cells invading the ...