Harlequin Great Danes are Great Danes with a special harlequin coloration, identified as white fur with large black patches. They are the most difficult color of Great Dane to breed.

Beautiful black-and-white dog breeds. Are you in love with the striking spots of the Dalmatian but think its energy level and size won’t suit your compact condo and low-key lifestyle?

Biologists have spotted the "starry night" harlequin toad in Colombia for the first time since 1991 after the species was largely wiped out by a ... characterized by its black and white spots, ...