Researchers have uncovered a surprising connection between a cancer-related signaling pathway and the blood-brain and blood-retina barriers.

A University of Minnesota Medical School-led research team has discovered that a cancer signaling pathway has previously ...

Novartis has inked a deal with China-based biotech Sironax that gives the pharma the exclusive option to acquire the ...

The researchers found that a protein called hypoxia-inducible factor (HIF) builds up in retinal cells during episodes of low ...

Two examples of FDA-approved intracameral implants are Durysta (Allergan) and iDoseTR (Glaukos), both of which provide ...

Patients, especially contact lens wearers, may develop microplastic toxicity and exhibit symptoms such as dry eye, a study ...

Advancements in polymer science are transforming the retinal disease treatment landscape, addressing clinical challenges such ...

Hypoglycemia can cause the breakdown of the blood-retinal barrier, worsening diabetic retinopathy through HIF accumulation. Diabetic mice exhibit higher HIF levels during hypoglycemia, leading to ...

Researchers are planning future studies on HIF, the breakdown of the blood-retinal barrier and 32-134D, and hope to conduct clinical studies of 32-134D in patients with diabetic retinopathy.

“By surface-modifying targeted ligands, liposomes could cross the blood-eye barrier for precise drug delivery.” With additional studies, the authors believe that liposomes could one day allow ...

During an interview with dvm360 prior to the Fetch Long Beach Conference in Long Beach, California, Jennifer Sheahan, DVM, DACVO, recounts cases where dietary indiscretions, such as feeding a dog ...

It is also difficult to use systemic therapies because the blood-eye barrier necessitates a large amount of systemic dosing which may cause untenable side effects.