Using advanced proteomics technologies, research teams from the Shanghai Institute of Nutrition and Health at the Chinese ...

Researchers found the therapy downregulated VEGF expression and improved retinal thickness in neovascular age-related macular degeneration patients.

Cas9, the first Cas protein repurposed for cutting DNA, introduces double-strand breaks that recruit DNA repair machinery. Despite its successes, the CRISPR-Cas9 system has several limitations, ...

pyogenes bacterium. The system had already been shown to only need a single Cas protein to cut up virus DNA, but Dr. Charpentier discovered that the small RNA molecule, now named trans-activating ...

The human gut is home to trillions of microbes that not only aid in digestion, but also play a key role in shaping our immune ...

In gene and cell therapy, RNP-mediated CRISPR gene editing is quickly emerging as the new norm. For many gene editing firms, GenScript has created hundreds of Cas9, Cas12a, Cas13a, MAD7, ABE, CBE ...

and VI), a single Cas protein effector recognizes and cleaves DNA. 9 After characterizing CRISPR’s role as a defense mechanism in bacteria, researchers soon realized that they could harness this ...

The University of Bayreuth's Biomaterials research group has, for the first time, successfully applied the CRISPR-Cas9 ...

Study in mice shows how a host-elicited factor benefits gut immunological homeostasis by selectively targeting commensal ceramide molecules.

Currently, most studies on protein structure and activity are conducted ... of Chemical Physics of the Chinese Academy of ...