CD27 and CD40 costimulatory molecules and TILs expressing activation marker CD38 in the tumour were also correlated with ... value of densities of tumour-infiltrating CD3 + T cells and CD20 + B cells ...

The first dose of KJ-C2320, an allogeneic chimeric antigen receptor (CAR) T-cell therapy targeting CD38, has been administered to a patient ... which targets CD19 and CD20, for the treatment of B-cell ...

The company will halt further development of imvotamab or CD20 x CD3 and IGM-2644 or CD38 x CD3, both IgM-based bispecific antibody T cell engagers, for autoimmune diseases. Imvotamab or CD20 x ...

Enrollment of cohorts receiving IDP-023 in combination with monoclonal antibodies targeting CD20 or CD38 is underway. In August, Indapta announced FDA clearance of its IND of IDP-023 in ...

Imvotamab (CD20 x CD3) trials in rheumatoid arthritis, systemic lupus erythematosus and myositis ongoing; initial clinical data expected by mid-2025 – – IGM-2644 (CD38 x CD3) expected to enter ...

– Imvotamab (CD20 x CD3) trials in rheumatoid arthritis, systemic lupus erythematosus and myositis ongoing; initial clinical data expected by mid-2025 – – IGM-2644 (CD38 x CD3) expected to enter ...

The 5 immune cells that seem to be involved with increased PAH risk are CD11b on basophil, CD20– CD38– AC, CD4 Treg AC, FSC-A on T cells, and native double negative (CD4– CD8–) %T cell.

Study participants were required to have received three or more prior lines of therapy, including a prior proteasome inhibitor, immunomodulatory drug and anti-CD38 monoclonal antibody.

The company also works with CD38-CAR-NK cells targeting CD38.CD38 is a surface protein commonly found on the surface of multiple myeloma cells and other hematologic malignancies. ... Poseida is also ...

There is no author summary for this article yet. Authors can add summaries to their articles on ScienceOpen to make them more accessible to a non-specialist audience. [1 ] departmentDepartment of ...

and plasmablasts (CD19+CD38+++IgD-CD27+CD20-) were assessed by multicolor flow cytometry. Results In pts with SLE, compared to healthy donors was found the higher percentage and abs level of memory B ...

The combination of chemotherapy with a naked anti-CD20 antibody (eg, rituximab ... substantially improved due to the introduction of proteasome inhibitors, IMiDs, and CD38-targeting antibodies; ...