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Team identifies key regulator blocking immunotherapy, paving the way for a new lung cancer treatmentThe mechanism is believed to involve DDX54 suppression inactivating signaling pathways such as JAK-STAT, MYC, and NF-κB, thereby downregulating immune-evasive proteins CD38 and CD47. This also ...
Prostaglandin E2 (PGE2), a bioactive lipid derived from arachidonic acid, mediates a broad range of physiological processes ...
Sterols, such as cholesterol in our bodies or ergosterol in yeast cells, are among the most abundant lipids in eukaryotic ...
More information: Feng-Rui Zhang et al, Distinct oxytocin signaling pathways synergistically mediate rescue-like behavior in mice, Proceedings of the National Academy of Sciences (2025). DOI: 10. ...
It's possible that the White House may be looking to replace Defense Secretary Pete Hegseth after critics warned that a pair of controversial Signal chats risked compromising US national security.
Pete Hegseth just can’t stop himself from using Signal. The defense secretary reportedly installed the encrypted-but-unclassified messaging app on a desktop computer in his Pentagon office to ...
on Monday signaled he wouldn't tolerate Defense Secretary Pete Hegseth allegedly once again sharing sensitive information about military operations in a Signal group chat. "If the reporting is ...
LIBREVILLE, Gabon (AP) — Gen. Brice Oligui Nguema was sworn in as the fourth president of the Republic of Gabon on Saturday, signalling a return to constitutional order in the country after ...
New research from UTHealth Houston reveals that substance use disorders accelerate biological aging in the brain through substance-specific molecular mechanisms. The study, published in Genomic ...
Long-lived IgG-producing plasma cells can be targeted by means of their expression of CD38. Alternatively ... and a regulator of cellular pathways of immunity associated with myeloid cells.
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