News

GEN - Genetic Engineering and Biotechnology News4d
Systemic Sclerosis Organ Damage Revealed Through scRNA-Seq
RNA-seq and spatial transcriptomics showed immune cell subsets that drive kidney and lung complications in systemic sclerosis ...
Designing better bispecific T-cell engagers for cancer immunotherapy
Kennedy researchers have uncovered key design parameters for bispecific T-cell engagers (TcEs)—a class of cancer ...
European Medical Journal2d
Mitigation of Immune Dysfunction in Patients with Sustained Suppression of Hepatitis B Surface Antigen After siRNA Treatment
A chronic hepatitis B (CHB) infection is characterised by host immune dysfunction related to a high viral antigen load. The restoration ...
eLife5d
CARD8 inflammasome activation during HIV-1 cell-to-cell transmission
During cell-to-cell spread, HIV-1 protease activity triggers CARD8 inflammasome activation and IL-1β release from macrophages, which may contribute to inflammation and chronic immune activation.
The Lancet4d
CD19-targeted CAR T-cell therapy for treatment-refractory autoimmune neuropathies
Severe autoimmune-mediated neuropathies, such as chronic inflammatory demyelinating polyradiculoneuropathy (CIDP) and ...
Frontiers2d
Exploring Unconventional T Cells and CAR-T Cells in Cancer Immunotherapy
In the field of cancer immunotherapy, unconventional T cells (UCTs) and Chimeric Antigen Receptor (CAR) T cells have emerged as promising areas of research ...
The American Journal of Managed Care6d
EHA 2025 Late-Breakers Reflect Diversity of Hematology Topics, From RedirecTT-1 Combo to Frailty Scales
The late-breaking abstracts presented on the last day of the 2025 European Hematology Association (EHA) Congress show “what a vibrant clinical specialty we’re in,” according to session cochair Brian ...