Talin is a protein that plays an important role in the immune system by activating integrins, receptors that help cells ...

B-cell acute lymphoblastic leukemia (B-ALL) is the most common cancer in children, accounting for around 85% of pediatric ...

Researchers at the University of Michigan designed an optimized viral protein able to boost the antitumor function of T cells. The project stemmed from observations on the particular system employed ...

The initial decision concerning which type of T effector cell will be induced ... The activity of chemokines in inducing activation of myeloid cells is well established 38 and chemokine-mediated ...

Figure 2: Binding of B7-H1 to CTLA4, ICOS and CD28. We measured the amounts of IL-2, IL-4, IFN-γ and IL-10 produced by T cells after stimulation with B7-H1Ig, B7-1 immunoglobulin (B7-1Ig ...