Antiretroviral therapy (ART) initiated in the acute phase of HIV infection (AHI) results in a smaller viral reservoir. However, the impact of early HIV-specific T-cell responses on long-term reservoir ...

Capstan Therapeutics scientists demonstrate that lipid nanoparticles can engineer CAR T cells within the body without ...

Whether antiretroviral therapy (ART) is always completely suppressive, or HIV might continue to replicate at low levels despite ART in some people with HIV (PWH), is still debated. Here, we ...

ALTB-268 demonstrated therapeutic potential in murine models of colitis and GvHD, supporting its role as an immune checkpoint enhancer in T cell-mediated inflammatory diseases Findings reinforce ...

A new nanozyme-powered TB test improves detection in people with HIV, offering rapid, electricity-free diagnosis via a beetle ...

There are two ways that HIV patients’ bodies can keep the virus under control after they stop antiretroviral therapy, a new ...

(12/20) complete response rate after treatment with EO2463 in combination with lenalidomide and rituximab (R2) <li /> EO ...

CD8-positive T cells are a critical subpopulation of MHC class I-restricted T cell and are mediators of adaptive immunity. They include cytotoxic T cells, which are important for killing cancerous ...

Researchers use targeted lipid nanoparticles loaded with mRNA to reprogram T cells to fight autoimmune diseases ...

CD4-positive T cells; CD8-positive T cells; Gammadelta T cells; NKT cells; T-cell receptor; Latest Research and Reviews. Iron deficiency causes aspartate-sensitive dysfunction in CD8 + T cells.

Van Andel Institute scientists and collaborators have discovered a potential treatment target that may re-energize ...