Antiretroviral therapy (ART) initiated in the acute phase of HIV infection (AHI) results in a smaller viral reservoir. However, the impact of early HIV-specific T-cell responses on long-term reservoir ...

In a human-mouse xenogeneic GvHD (xGvHD) model, ALTB-268 significantly improved survival, reduced disease severity score and body weight loss, and decreased human CD4+ and CD8+ T cells, while ...

Targeted Oncology connects oncology professionals with updates on immunotherapy, biomarkers, cancer pathways, and targeted ...

The following highlights showcase late-breaking research presented at the European Association for the Study of the Liver ...

Capstan Therapeutics scientists demonstrate that lipid nanoparticles can engineer CAR T cells within the body without ...

CD8-positive T cells are a critical subpopulation of MHC class I-restricted T cell and are mediators of adaptive immunity. They include cytotoxic T cells, which are important for killing cancerous ...

There are two ways that HIV patients’ bodies can keep the virus under control after they stop antiretroviral therapy, a new ...

CAR-T cells, which are genetically programmed to specifically recognize and kill target cells, have altered the therapeutic ...

A chronic hepatitis B (CHB) infection is characterised by host immune dysfunction related to a high viral antigen load. The restoration ...

The study reviews CAR-T cell advancements in lymphoma treatment, addressing T cell exhaustion and tumor immune evasion with ...

Researchers sought to determine whether CAR-T therapy could improve HR-QoL scores for patients with relapsed or refractory multiple myeloma.