A pair of recent studies from the laboratory of Bin Zhang, MD, Ph.D., the Johanna Dobe Professor of Cancer Immunology, have ...

Like much of Dr. Xue's other work, the latest paper focuses on CD8 + T cells ... these effector cells eventually enter a state of "exhaustion" which makes them less and less effective.

Q1 2025 Earnings Call Transcript May 15, 2025 Operator: Thank you for standing by. My name is Rochelle, and I will be your ...

At this time, I would like to welcome everyone to the MiNK Therapeutics first quarter 2025 financial results. After the speaker remarks, there will be a question-and-answer session. If you would like ...

A new study found that taurine, an amino acid often added to energy drinks, may fuel the growth of leukemia cells. But can ...

Dr Belinda Kaskow explores the benefits of investigating the early stages of immune dysregulation in MS to enhance prevention ...

HBV-specific and HCV-specific CD8 + T cells exhibit distinct metabolic profiles that correlate with severity of exhaustion. Severe mitochondrial depolarisation despite high glucose uptake is present ...

Conclusions The possibility to distinguish patient cohorts with different capacity to respond to immune modulatory compounds in vitro by a simple analysis of the phenotypic CD8 T cell exhaustion ...

Sickle cell disease (SCD) altered CD8+ T-cell chromatin architecture, triggering ferroptosis and weakening antitumor immunity ...