An engineered viral protein enhanced the anticancer function of T cells in mice, suggesting a new strategy to improve ...

A pair of recent studies from the laboratory of Bin Zhang, MD, Ph.D., the Johanna Dobe Professor of Cancer Immunology, have ...

A new study found that taurine, an amino acid often added to energy drinks, may fuel the growth of leukemia cells. But can ...

"Since taurine is a common ingredient in energy drinks and is often provided as a supplement to mitigate the side effects of ...

1Center for Immunology, University of Minnesota Medical School, Minneapolis, Minnesota. 2Department of Microbiology and Immunology, University of Minnesota Medical School, Minneapolis, Minnesota.

Like much of Dr. Xue's other work, the latest paper focuses on CD8 + T cells ... these effector cells eventually enter a state of "exhaustion" which makes them less and less effective.

When cancer continues to advance despite aggressive treatment like this, it's due in part to immune suppression and T cell exhaustion that make anti-cancer therapies less effective. To combat ...

CAR T-cell exhaustion panel, CAR T-cell persistence panel, etc.), DNA methylation [EPICART signature (62)], cytokine secretion (cytotoxic cytokines, Th2-skewed cytokines), surface marker expression ...

The mouse-based study, published in the Journal of Experimental Medicine, uncovered a new way to enhance stem cell-like memory CD8+ T cells following vaccination, pointing to a future where more ...