Autoimmunity to antigens of the central nervous system is usually considered detrimental. T cells specific to a central nervous system self antigen, such as myelin basic protein, can indeed induce ...

The autonomic nervous system plays an important role in the modulation of cardiac electrophysiology and arrhythmogenesis. Decades of research has contributed to a better understanding of the anatomy ...

“These findings represent a significant advancement toward new treatments for previously challenging CNS diseases,” said Hiroyuki Sonoda, Ph.D., Director, Senior Managing Executive ...

Dyno-ahq is optimized for widespread and efficient delivery to the brain and throughout the CNS upon IV injection. With enhanced CNS delivery efficiencies compared to prior Dyno capsids ...

Central nervous system (CNS) diseases involve complex pathophysiology, gradual symptom onset, and significant challenges in therapeutic evaluation. Aging populations and increasing life and work ...

The antitumour response we uncovered in the leptomeninges raises the possibility that other immune responses there might diverge from their typical behaviour outside the central nervous system.

v. Avadel CNS Pharma., 2025 WL 1298920, — F.4 th — (Fed. Cir. May 6, 2025), addressed the scope of the 35 U.S.C. § 271(e)(1) “safe harbor” provisions for certain clinical trials and ...

(2) The analysis was typically conducted using investigational compounds and nonapproved drugs. (3) Non-CNS drugs were most often neglected in the analysis. (4) The computed property source was not ...

The feasibility of a computer-aided scoring system based on artificial intelligence to detect and classify morphological changes in neuroglial cells was assessed in this study. The system was applied ...

These characteristics make them an attractive means of measuring disease-related processes within the central nervous system (CNS), as they cross the blood–brain barrier (BBB) and can be captured in ...