This important study demonstrates the potential of synthetic gene circuits to detect and target aberrant RAS activity in cancer cell lines. The circuit design is novel and the evidence supporting the ...

Due to proteostasis stress induced by aging or disease, misfolded proteins can form toxic intermediate species of aggregates and eventually mature into less toxic inclusion bodies (IBs). Here, using a ...

These include some obvious mechanical activities such as endocytosis, cell motility and membrane resealing, but also others, such as replication and transcription. Taking the motor proteins as an ...

A team led by UT Southwestern Medical Center researchers has identified a key mechanism responsible for endosomal recycling ...

Neurons are cells in the body that are responsible for transmitting electrical signals through the nervous system. Different types of neurons affect the ability to move, which begins as an impulse, or ...

Article Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to ...

The pleura (plural: pleurae) is a two-layered membrane that covers the lung ... Pleural fluid is secreted by the specialized cells in the pleura called mesothelial cells. The fluid allows the layers ...

Cummins has introduced a new leading-edge parts label system, featuring hologram technology, to help customers confirm they are buying the genuine product. The development of holograms, whose effects ...

The American hitmaker, 35, has parted ways with the label after they were embroiled in a series of spats. Bebe previously had a number one hit in 2022 when she joined forces with David Guetta for ...

Biologists had long believed that bringing order and organization to the chaos of molecules inside a cell depended on membrane-bound ... in condensates have parts that are more open and floppy ...

helping the cells stay healthy by getting rid of damaged parts and recycling useful components. The process involves formation of a vesicle called the autophagosome, which encapsulates the ...