TMEM67 performs dual functions in cells thanks to cleavage into separate isoforms. One TMEM67 isoform migrates to the ciliary transition zone and becomes a building block for cilia.

New research by Sumeda Nandadasa, PhD, reveals how a key protein associated with Meckel-Gruber syndrome, nephronophthisis, ...

Jim FessendenUMass Chan Medical SchoolNew research by Sumeda Nandadasa, PhD, reveals how a key protein associated with Meckel-Gruber syndrome ...

New research by Sumeda Nandadasa, Ph.D., reveals how a key protein associated with Meckel-Gruber syndrome, nephronophthisis, ...

As expected, the mice had impaired cilia formation and function and high levels of aldehydes.” The mice lacking ALDH1A1 were also at increased risk of developing a serious lung infection when ...

Dynein-2 is one of the motors that move the intraflagellar transport (IFT) trains ― large protein complexes that are needed for the assembly and function of eukaryotic cilia and flagella.

Smoking not only exposes you to potentially life-threatening illnesses but it also increases your susceptibility to ordinary ...

Teeth are called incisors, canines, premolars, and molars. Each type of tooth has a specific function, including biting, chewing, and grinding food. Teeth are made up of different layers ...

“Our approach involves removing cells from trachea tissue — either from animal models or human donors — and implanting hPSCs that regenerate a functional tissue,” Kim explained. “This trachea graft ...

An 86-year-old man was evaluated for chronic cough and right lower lobe (RLL) mass. His medical history was significant for severe chronic obstructive lung disease (COPD). He had smoked one pack of ...