sBT of 20 ug/L or higher is one of the minor criteria for systemic mastocytosis and typically increases the suspicion that a patient could have a primary clonal mast cell disorder. Of note, though ...

The PRISM study included a meaningful number of respondents across seven European countries, providing important insights to tailor disease ... of SM and other clonal mast cell diseases ...

Here, authors show through clonal analysis that UM171 also biases the differentiation trajectories of hematopoietic progenitor cells in culture. Mast cells serve as sentinels for mucosal infection.

Tumor-infiltrating clonal hematopoiesis is associated with worse outcomes in patients with cancer, new research suggests.

Kounis syndrome is a ubiquitous disease affecting individuals of any ... We had previously suggested that a threshold level of mast cell content (tryptase, chymase and so on) exists [15] above ...

Next steps include the production of more mitochondrial disease-free egg cells and the generation of healthy progeny in an animal model. The research was conducted in the New York Stem Cell ...

Nearly half of sequencing data labeled as endometriosis lacks true disease representation, highlighting the urgent need for more diverse and accurate tissue sampling to advance research in this ...

This collaboration supports the development of multiple Treg cell therapy drug candidates targeting severe immune disorders. AGC Biologics will provide lentiviral vector (LVV) material using its ...

Astrocytes are recognized as key regulators of neuroimmune interactions, significantly contributing to both the development ...

It has been nearly two years since Pfizer’s sickle cell disease (SCD) therapy Oxbryta was approved in the UK, but patients will now be able to access the treatment after an agreement was reached ...