Scientists have uncovered a critical role for rapid DNA repair in maintaining genome stability. A new study reveals that ...

A unique feature of HR is that it repairs the damage to the DNA in a highly accurate way. In eukaryotic cells (those with a ...

This landmark study describes the structure of the human RAD51 filament with a recombination intermediate called the displacement loop (D-loop). Using cryogenic structural, biochemical, and ...

Most biochemistry labs that study DNA isolate it within a water-based solution that allows scientists to manipulate DNA without interacting with other molecules. They also tend to use heat to ...

PAX3 is a transcription factor (proteins involved in converting DNA into RNA) that drives melanoma progression by promoting ...

Researchers have used a personalised base-editing gene therapy to successfully treat an infant with carbamoyl-phosphate ...

By creating a more true-to-life representation of DNA's environment, researchers at Northwestern University have discovered that strand separation - the essential process a "resting" double helix ...

DNA damage and repair refers to the creation and correction of DNA lesions that threaten genome integrity. Because DNA replication errors or environmental agents that damage DNA can introduce ...

The shooting of 85-year-old retired farmer Lowell Badger was the end of a night “of bad decisions”. That was how Special ...

The yeast nuclear endonuclease Rnt1 has a well-characterized role in the maturation of many ncRNA precursors. However, the scope and consequence of its function in mRNA degradation pathways is much ...