Researchers developed a standardized, physiologically relevant model to maximize its potential for studying disease mechanisms and evaluating potential therapies, marking a critical advancement over ...

That may be because most mouse models of Alzheimer's disease harbor the Swedish mutation. This has so far hindered efforts to study the beneficial effects of the Icelandic mutation. Now ...

HGFM is a high-order correlation-driven foundation model for brain disease diagnosis and effectively improves prediction performance. Specifically, HGFM first performs brain functional network link ...

The discriminative performance of the model for mortality events was validated through calibration plots and receiver operating characteristic (ROC) curves highlighting CRP as a key biomarker ...