A major regulator of neutrophil production and survival is the cytokine granulocyte colony-stimulating factor (G-CSF). Treatment with G-CSF can exacerbate underlying inflammatory diseases in ...

3 University of Colorado School of Medicine, Aurora, Colorado, USA Objective Eosinophils reside in the colonic mucosa and increase significantly during disease. Although a number of studies have ...

A double-labelling approach was taken to localise CRH expression in immune cells (including dendritic cells, mast cells, lymphocytes, enterochromaffin cells and eosinophils) in the intestine by ...

We have recently described three transcriptome-associated clusters (TACs) in the U-BIOPRED asthma cohort using hierarchical clustering of genes differentially expressed in sputum between ...

Eosinophilic esophagitis (EoE) occurs when white blood cells called eosinophils build up in the esophagus, the tube that moves food and liquids from the throat to the stomach. This buildup of ...

ECP is a marker of the activity and turnover of the eosinophil granulocyte. [4] Our study was designed to examine P-ET levels in paediatric patients newly diagnosed with mild persistent bronchial ...

The eosinophils release inflammatory substances that can damage the esophagus's tissue, causing symptoms like difficulty swallowing. The exact cause of EoE is not fully understood, but a ...

eosinophil peroxidase; GM-CSF, granulocyte-macrophage colony-stimulating factor; PAF, platelet-activating factor; MMP-9, matrix metalloproteinase-9; IFN-λ1, interferon-λ1. Figure 4 Physical contact ...

Eosinophils activated by IL-5 contribute to oxidative stress ... chemotactic and immune activating proteins (18–20). TSLP, IL-33, GM-CSF (granulocyte-macrophage colony-stimulating factor) and IL-25 ...

The Eosinophil project: We investigate how the white blood cell, the eosinophil granulocyte, interacts with and regulates the functions of another type of white blood cell, the T-lymphocyte. Patients ...