These large-scale genome changes may not only affect the evolution of cell differentiation, as has been proposed, but may alter the epigenetic ... Additional regulation of axon regeneration ...

such as the capacity for robust axon outgrowth, are lost. The genetic and epigenetic programs controlling prenatal development are well studied, but our understanding of the transcriptional mechanisms ...

Image Caption: Epigenetic regulation of receptors. Genes & Diseases publishes rigorously peer-reviewed and high quality original articles and authoritative reviews that focus on the molecular ...

gene regulation and epigenetics, cancer biology, immunity and infection, neuroscience, disease-specific animal models, gene and cell-based therapies, and regenerative medicine. Scopus CiteScore: 7.3 ...

Analysis of the presence of inflammatory proteins during the repair process suggested that PDGF-BB administration not only promotes axon regeneration, but also reduces inflammation. RNA sequencing ...

Analysis of the presence of inflammatory proteins during the repair process suggested that PDGF-BB administration not only promotes axon regeneration, but also reduces inflammation. RNA sequencing ...

Imaging shows regeneration of sensory axons four weeks after a spinal cord injury in an adult mouse injected with PDGF-BB at the lesion site. COLUMBUS, Ohio – Capitalizing on the flexibility of ...

In several neurodegenerative diseases, it is the long neuronal processes (axons) and their synapses (with other neurons or muscle) that first show signs of pathology and degenerate. Still, these ...

regeneration in response to injury, and the corruption of this capacity by cancer stem cells. This Research Topic seeks to improve understanding of the genetic and epigenetic regulation of these ...