The FDA has granted fast-track designation to nipocalimab for the treatment of Sjögren’s disease, according to a press ...

FDA grants Fast Track designation to Johnson & Johnson’s investigational therapy nipocalimab for the treatment of moderate-to-severe Sjögren’s disease, which could be the first targeted therapy ever ...

Fc-gamma receptors (FcγRs) are a group of cell surface proteins found on a range of immune cells. These proteins represent the primary cell signaling method between IgG antibodies and our immune ...

New agents targeting endocrine therapy and CDK4/6 resistance in hormone receptor–positive breast cancer are in development.

Largest safety data set on FcRn blocking demonstrates consistent, favorable safety profile of VYVGART and VYVGART HytrulogMG patients on VYVGART achieve rapid, substantial, and sustained efficacy ...

Argenx (ARGX) announced clinical trial and real-world data for Vyvgart and Vyvgart Hytrulo will be presented at the American Academy of ...

X-ray and nuclear magnetic resonance studies have also revealed conformational changes that occur on IgE binding to its high-affinity receptor FcεRI (high-affinity Fc receptor for IgE ...

Neonatal Fc receptor (FcRn) inhibitors like efgartigimod (Vyvgart) and rozanolixizumab (Rystiggo), which reduce the levels of circulating pathogenic immunoglobulin G autoantibodies by accelerating ...

Opens in a new tab or window Recently approved treatments for generalized myasthenia gravis (gMG), including complement and neonatal Fc receptor (FcRn) inhibitors, offer a new treatment paradigm ...

Concentration-dependent cleavage of IgE B cell receptor. Concentration-dependent reduction of expression of the high-affinity IgE Fc receptor, on bone marrow-derived mast cells from humanized mice.

Seismic Therapeutic, Inc., the machine learning immunology company, today announced the dosing of the first healthy subject cohort in a Phase 1 clinical trial of S?1117, a novel engineered Fc-fused ...