Imagine losing your ability to speak or move, yet still having so much to say. For Brad G. Smith, this became his reality ...

John Driskell Hopkins has lived with ALS for 3½ years. The Zac Brown Band musician updates us and shares a new song for his ...

Amy Holden Jones’s 1983 melodrama should have established her as a major Hollywood director, but, as a female filmmaker, she ...

Scientists from St. Jude Children's Research Hospital and Washington University in St. Louis report mechanistic insights into ...

Genetic mutations in many forms of ALS lead to early problems with the transport and function of mitochondria, a study found.

Learn how a new genetic therapy could transform treatment for rare ALS—keep reading for remarkable patient outcomes.

Typically, the goal of ALS treatments is to slow the disease or halt progression. But new data from the antisense oligonucleotide (ASO) jacifusen for FUS-ALS show that two patients went beyond the ...

Some patients with a rare form of ALS benefited from an experimental therapy, with biomarker evidence of reduced injury to neurons and even limited functional recovery.

An experimental drug known as ulefnersen has shown remarkable efficacy in treating a rare, aggressive form of ALS ...

When Columbia neurologist and scientist Neil Shneider speaks to his ALS patients who volunteer for experimental therapies, he ...

This experimental drug could help young people with a rare and aggressive form of ALS - Researchers say a full-scale clinical ...

Other potential risk factors include: Familial ALS (FALS) is a genetic form of ALS, meaning individuals inherit it. It accounts for approximately 10% of ALS cases, making it less common than ...