Protective efficacy against subsequent controlled human malaria infection was observed in 8 of 9 participants (89%) in the GA2 group, in 1 of 8 participants (13%) in the GA1 group, and in 0 of 3 ...

Study: Single immunization with genetically attenuated Pf∆mei2 (GA2) parasites by mosquito bite in controlled human malaria infection: a placebo-controlled randomized trial. Image Credit ...

Researchers at Leiden University Medical Center tested a LARC1 parasite with the deletion of the Mei2 gene alone (called GA2 by the Leiden team) and demonstrated that this provided 90% protection ...