Studies on transgenic mice that express a mutant gene associated with one of the diseases have demonstrated that glial cells play a pivotal role in disease pathogenesis. For example, mutant ...

Importantly, the ways in which glial cells work have a lot to do with what happens in AD patients. For example, glial cells are known to clear away abnormal build-up of protein, accompanied by an ...

There are two fundamentally different cell types in the brain, neurons and glial cells. The latter, for example, insulate the 'wiring' of nerve cells or guarantee optimal working conditions for them.

Astrocytes and Schwann cells, for example, may also prune synaptic connections. But despite the commonalities among different subsets of glia, researchers are starting to realize that there’s little ...

We focus here on examples, especially ALS and type ... with toxicity originating from damage both within Purkinje cells and within neighboring glial and neuronal cells as direct contributors ...

Glial cells are the commonest type of cells in the human brain and spinal cord. They surround neurons but are distinct from them and play an important supporting role – for example, in material ...

Many sensory nerve endings in the skin associate with glial cells that form the innermost part of larger structures, for example, the Pacinian corpuscle. Lastly, the complex ganglia of the enteric ...

It might take a normal mouse four or five attempts to learn the correct route, for example. But a mouse with human brain cells could get it on the second try. Glial cells — those boring glial ...

The researchers had previously demonstrated that healthy human glial cells replaced unhealthy mouse glial cells when transplanted into mouse models of Huntington’s disease, a rare and fatal ...