The results of experiments in mice models were "astounding," said biochemist Suzanne Pfeffer of Stanford University.

More than 90% of patients achieved clinically meaningful weight reduction compared to placebo in a phase 3 trial of ecnoglutide.

A diabetes medication that lowers brain fluid pressure has cut monthly migraine days by more than half, according to a new ...

The PI3K signaling pathway is induced by several growth factors and other hormones. For instance, activation of insulin receptor causes phosphorylation of tyrosine residues in insulin receptor ...

News Release 17-Jun-2025 New hormonal pathway links oxytocin to insulin secretion in the pancreas Peer-Reviewed Publication Impact Journals LLC image: Figure 2. Relation of Oxt and glucagon.

Signaling Pathways Regulating Osteoblast Differentiation & Bone Formation Osteoblast differentiation is predominantly regulated by Wnts, which are mammalian homologs of the Drosophila secreted ...

Forkhead/winged helix transcription factor O-class member 1 (FoxO1) is a key mediator of insulin and glucagon signaling in control of glucose homeostasis. Although epigallocatechin gallate (EGCG) has ...

The NF-κB signaling pathway includes both classical and non-classical signaling pathways. The main difference is that the signaling pathway is activated differently. The classical NF-κB signaling ...

Semaglutide, a synthetic analog of glucagon-like peptide-1 (GLP-1), has garnered attention for its intriguing properties and potential implications in various r ...

In addition, the discovery of the IL-23/IL-17 pathway has contributed to a clearer understanding of the underlying mechanism of inflammatory diseases. At present, therapies for inflammatory diseases ...