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Claudin18.2 (CLDN18.2) expression and efficacy in pancreatic ductal adenocarcinoma (PDAC): Results from a phase I dose expansion cohort evaluating IBI343. 10-year follow up of a phase 2 clinical trial ...
EBC-129 has been granted FDA fast track designation for the treatment of pancreatic ductal adenocarcinoma, paving the way for ...
US FDA grants fast track designation to EDDC’s antibody-drug conjugate EBC-129 to treat pancreatic ductal adenocarcinoma: Singapore Thursday, May 29, 2025, 12:00 Hrs [IST] The E ...
It selectively targets a tumour-specific N-glycosylated epitope on both CEACAM5 and CEACAM6. The Fast Track Designation highlights the potential of EBC-129 to address critical unmet needs in ...
A study by researchers at the Interuniversity Institute of Bioinformatics in Brussels, the Structural Biology research group at Vrije Universiteit Brussel, and IBiTech–BioMMedA Group of Ghent ...
From boosting immunity to improving blood flow and pressure, beetroot is said to possess many health benefits. It is often ...
The novel antibody-drug conjugate EBC-129 has been fast tracked by the FDA for approval in pancreatic ductal adenocarcinoma.
O-GlcNAc modification plays important roles in metabolic regulation of cellular status. Two homologs of O-GlcNAc transferase, SECRET AGENT (SEC) and SPINDLY (SPY), which have O-GlcNAc and O-fucosyl ...
The Hidden Language of GlycansImagine a vast molecular conversation happening within and between cells—where sugar-based structures act as sophisticated messengers carrying critical biological ...