Figure 1. Mechanism of action of maraviroc. Before fusion of the HIV viral envelope and host cell membrane can occur, an HIV glycoprotein complex consisting of glycoproteins gp41 and gp120 must ...

Individual gp120 and gp41 subunits are colored in light and dark blue, respectively. The CD4 D1 domain (red) and ... Selection on CD4 is thought to be driven by the direct interaction between CD4 and ...