Figure 1. Mechanism of action of maraviroc. Before fusion of the HIV viral envelope and host cell membrane can occur, an HIV glycoprotein complex consisting of glycoproteins gp41 and gp120 must ...

Structures of solubilized HIV-1 envelope glycoprotein trimers suggest that the gp120 C-termini and gp41 membrane-proximal external regions (MPERs) and α9 helices assemble into a membrane-proximal ...

The HIV-1 gp120 glycoprotein is the main viral surface protein responsible for initiation of the entry process and, as such, can be targeted for the development of entry inhibitors. We previously ...

The 30-day mortality rate (4.2 percent) did not differ significantly from that of 3.5 percent reported in a recent comparison of stenting with PTCA. 34 In our patients, most of whom had an initial ...

The suggested mechanism of this interaction occurs through preferential binding to HIV-1 gp120 glycoprotein knobs because of the regular spatial relationships of attached NPs, the center-to-center ...

Cryo-EM structural results of tuna P-glycoprotein revealed multiple inward-facing apo conformations and only a single open inward-facing bound conformation in the presence of DDT. We therefore suggest ...

Background We evaluated the seroprevalence of myelin oligodendrocyte glycoprotein immunoglobulin G1 (MOG-IgG) and associated clinical features of patients from a large adult-dominant unselected cohort ...

Oral anticoagulants (OACs) are medications commonly used in patients with atrial fibrillation and other cardiovascular conditions. Both warfarin and direct oral anticoagulants are susceptible to ...

Objective Myelin oligodendrocyte glycoprotein-associated disorders (MOGADs) are a rare new neurological autoimmune disease with unclear pathogenesis. Since a linkage of the disease to the human ...

Adipokine zinc-alpha-2-glycoprotein as a novel urinary biomarker presents earlier than microalbuminuria in diabetic nephropathy. J Int Med Res 2016;44:278-86. 31 Rao PV, Lu X, Standley M, Pattee P, ...