Adoptive Cell Transfer (ACT) includes a class of immunotherapy approaches to treat cancer.  This procedure focuses on a ...

Cytotoxic T cells are star players in the adaptive immune system, enforcing protection against invading viruses or cancer cells. However, evidence has been mounting that the cells may also deal a ...

Specific host factors, such as immune cell activity, sex hormones and microbiota composition, influence the ability of Staphylococcus aureus bacteria to colonize the gut of mice.

This study presents a valuable finding on the direct cytotoxic effects of DuoHexaBody-CD37 in diffuse large B-cell lymphoma, mediated via SHP-1 activation and antibody clustering, independent of ...

This occurs in specific lymph node areas that are accessed thanks to CXCR3 expression on CD8 T cells. There, they receive IL-2 from CD4 helper T-cells. Without this signal, CD8 T-cells cannot ...

This occurs in specific lymph node areas that are accessed thanks to CXCR3 expression on CD8 T cells. There, they receive IL-2 from CD4 helper T cells. Without this signal, CD8 T cells cannot ...

Specifically, cytotoxic T cells target infected cells, while helper T cells and B cells drive antibody production. A critical component of this process is the delivery system- most commonly LNPs ...

A recently developed cancer treatment called chimeric antigen receptor T-cell therapy (CAR T-cell therapy, for short) offers hope to people whose diffuse large B-cell lymphoma (DLBCL) has proved ...

If you or a loved one has diffuse large B-cell lymphoma (DLBCL) that is no longer responding to treatment or came back after treatment, chimeric antigen receptor (CAR) T-cell therapy may be an option.