When Treg cells are produced, they are trained to recognize specific peptides, including self-peptides from the body. When dendritic cells present a self-peptide, the peacekeeper Treg cells trained to ...

Discovery of innate immune receptor "brake" Siglec-E offers a novel therapeutic target to prevent organ transplant rejection ...

A recently developed cancer treatment called chimeric antigen receptor T-cell therapy (CAR T-cell therapy, for short) offers hope to people whose diffuse large B-cell lymphoma (DLBCL) has proved ...

If you or a loved one has diffuse large B-cell lymphoma (DLBCL) that is no longer responding to treatment or came back after treatment, chimeric antigen receptor (CAR) T-cell therapy may be an option.

EchoBack CAR T-cells are smart immune warriors that respond to ultrasound to fight cancer longer and more safely than ever before. They promise a big leap in treating solid tumors. Credit: ...

Lymphocytes are a type of white blood cell produced in bone marrow that play a crucial role in your immune system. There are several types—called T cells, B cells, and natural killer (NK) cells—that ...

CD4 T helper cells are a type of white blood cell called a lymphocyte that serves an important role in your immune system. These cells help defend the body against infection by directing other "killer ...

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1Department of Orthopaedics and Traumatology, School of Clinical Medicine, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Pokfulam, Hong Kong SAR, China.

However, the role of tumour-infiltrating B cells (TIBs) remains controversial. Here, we investigate the impact of TIBs and their interaction with T cells on HCC patient prognosis. Design Tissue ...