Mechanism whereby T cell plasticity, a process originating in the gut and aided by gut microbiota, promotes autoimmunity at gut-distal sites.

CD4 T helper cells are a type of white blood cell called a lymphocyte that serves an important role in your immune system. These cells help defend the body against infection by directing other ...

Some, known as dendritic cells, take up proteins from foreign pathogens, chop them up into peptides called antigens, and display them on their surface. Another group, known as helper T cells, inspects ...

Newly discovered oncology drugs called “DNA-encoded tri-specific T-cell engagers,” or “DTriTEs,” engage the immune system ...

“Anktiva not only proliferates and activates the patient’s own NK cells and CD8+ killer T cells, but also activates CD4+ T helper cells, thus enhancing the proliferation of memory killer T cells. This ...

Creating cancer therapies based around natural killer cells could offer similar levels of efficacy to CAR-T therapies, but at around one hundredth of the cost. Researchers at MD Anderson Cancer ...

Using technology developed by Klebanoff’s group, the researchers were able to isolate killer T cells from healthy donors that recognize and react to the CLK3 neoantigen displayed on HLA-A*02:01. The ...

These lymphocytes, including B cells, CD4+ T cells (helper T cells), CD8+ T cells (cytotoxic T cells), and natural killer (NK) cells, play crucial roles in the immune system. The test helps assess ...