This study reveals that neutrophil extracellular traps (NETs) drive macrophage-derived chemokine production (CXCL9/10/11) to promote CD8+ T cell ...

These translational experiments with human monocytes were complemented with the assessment of BMS235 effects on human macrophages and fibroblasts. Indeed, an interesting regulation of ...

Monocyte-derived macrophages can replace all myeloid cells in the mouse brain, but only fetal-liver monocytes develop a true microglia identity. Monocyte origins shape their profile as brain ...

The counts include human trafficking because the defendants allegedly understood and exploited their victims' vulnerabilities, the suit claims.

Objective We aimed at investigating the effects of biliary epithelial cell-derived acute phase response protein orosomucoid 2 (ORM2) in shaping monocyte/macrophage response to liver injury. Design ...

BACKGROUND: Circulating monocytes largely contribute to macrophage buildup in atheromata, which is crucial for clearing subendothelial LDLs (low-density lipoproteins) and dead cells; however, the ...

Since human monocytes only circulate for about three days in the body, the researchers assume that the precursor cells of monocytes in the bone marrow also carry the epigenetic markers.

Immune memory plays a critical role in the development of durable antimicrobial immune responses. How precisely mRNA vaccines train innate immune cells to shape protective host defense mechanisms ...

As a control, we generated spheroids with human foreskin keratinocytes (HFKs) and inserted monocytes and T-cells. We first characterized the macrophage surface markers of TAMs derived from tumor ...

Images of tunneling nanotubes. Arrows pointing to the tunneling nanotubes. Credit: Dupont M., Tunneling nanotubes in immune cells, CC BY 4.0, Confocal image of day 13 HIV-1-infected human ...