Dendritic cells (DCs) are increasingly being explored as cellular vaccines for tumor immunotherapy, since they provide an effective system of antigen presentation both in vitro and in vivo. An ...

Figure 2. Expression of E-prostanoid receptor 2 (EP2) and EP4 receptors in renal CD44+ cells. A, Reverse transcriptase polymerase chain reaction (RT-PCR) for EP2 or EP4 receptor expression. GAPDH was ...

Etokimab (I-Mab Biopharma), which is optimized for common IL-33 gene polymorphisms, has completed patient recruitment in its ...

A breach in the gut immunity and crossreactivity of the IgE antibodies with skin antigens or direct interaction with specific IgE, Fc receptors on Langerhans cells, mast cells, monocytes ...

Complex allergen sources contain only a limited number of allergens that induce IgE antibodies in more than 50% of the allergic individuals, so-called 'major' allergens. 'Minor' allergens are less ...

Dose-dependent, marked reductions in food intake and significant weight loss observed in obese cynomolgus monkeysBMF-650 compared favorably to published data of a leading GLP-1 RA candidateIND ...

Methods and Results— We examined the effects of statins on phagocytosis of antibody-coated red blood cells by cultured human monocytes and mouse peritoneal macrophages. Lovastatin, simvastatin, and ...

Once hailed as the future of immuno-oncology, it’s been a tough few months for any remaining fans of anti-TIGIT antibodies.