News

The American Journal of Managed Care5d
Rozanolixizumab for gMG Approved in Japan for Self-Administration
The approval marks the second international approval for rozanolixizumab (Rystiggo; UCB Pharma) for generalized myasthenia ...
The American Journal of Managed Care21d
FDA Approves Nipocalimab for Generalized Myasthenia Gravis
Nipocalimab joins a roster of several other currently approved FcRn receptor blockers—rozanolixizumab-noli (Rystiggo; UCB), efgartigimod alfa-fcab (Vyvgart; Argenx), and efgartigimod alfa and ...
C&EN22d
Design of an Fc Mutation to Abrogate Fcγ Receptor Binding Based on Residue Interaction Network Analysis
Institute of Chemical Processes, Seoul National University, Seoul 08826, Republic of Korea Department of Chemical and Biological Engineering, Seoul National University, Seoul 08826, Republic of Korea ...
rarediseaseadvisor28d
Most Nanoparticles Do Not Trigger Mast Cell Activation, Study Finds
Paclitaxel protein-bound, but not doxorubicin liposome injection, reduced the number of cells expressing Fc epsilon receptor I, the immunoglobulin E receptor. Researchers have developed and validated ...
The New England Journal of Medicine28d
Neonatal Fc Receptor — Biology and Therapeutics
Recently, a new class of therapeutics that disable the neonatal Fc receptor (FcRn), which protects IgG from degradation, has emerged to treat IgG-mediated autoimmune disease. 4,5 Here, we review ...
Independent Online28d
Simba won’t roar … Stellenbosch FC, Steve Barker cautiously optimistic about Caf Confed semi-final
It’s no secret that Stellenbosch were outplayed in their first-leg Caf Confederation Cup semi-final against Simba over the weekend, but trailing by just a single goal has given Stellies coach ...