Insulin resistance is concomitant with type 2 diabetes, obesity, hypertension, and other features of the metabolic syndrome. Because insulin resistance is associated with cardiovascular disease ...

Now, a study published in Cell Communication and Signaling describes new molecular mechanisms to understand insulin resistance in skeletal muscle and to outline future drug targets for DM2. The ...

Insulin resistance in the brain is associated with obesity, type 2 diabetes, and cognitive dysfunction. Insulin normally regulates appetite and metabolism through brain signaling, but resistance ...

PPARβ/δ upregulates the insulin receptor β subunit in skeletal muscle by reducing lysosomal activity and EphB4 levels. Cell Communication and Signaling , 2024; 22 (1) DOI: 10.1186/s12964-024 ...

Get Instant Summarized Text (Gist) New molecular mechanisms linked to insulin resistance in skeletal muscle have been identified, highlighting potential drug targets for type 2 diabetes. The study ...