Diabetes is a chronic metabolic disorder characterised by persistently high blood sugar levels (hyperglycaemia) caused by ...

A contractor digging into the earth where the rubble of a destroyed house had been cleared away in northern Syria stumbled ...

Better diagnosis and treatment The breakthrough was made using cutting-edge protein analysis, known as proteomics, to study how insulin affects muscle tissue. This approach enabled the team to map ...

Small molecules with big potential The two drugs used in this study are already approved to treat rare cancers. Tazemetostat, known under the brand name Tazverik, was approved by the U.S. FDA in ...

PPARβ/δ upregulates the insulin receptor β subunit in skeletal muscle by reducing lysosomal activity and EphB4 levels. Cell Communication and Signaling , 2024; 22 (1) DOI: 10.1186/s12964-024 ...

The story of the discovery of the hormone insulin, the elucidation of its role in controlling blood sugar levels and its development as a successful treatment for diabetes is a rich vein in the ...

Low-molecular-weight HA (LMW-HA), in particular ... 51 An in vitro study found that HMW/LMW-HA and insulin-growth factor I mitigated radiation-associated damage in keratinocytes, thus providing a ...

Protamine sulfate is available commercially for US$6550–10 800/kg. As the molecular weight of RHI and protamine sulfate is similar, insulin NPH API cost can be estimated by assuming it is 89% by mass ...

Insulin resistance occurs when your cells become less responsive to insulin, a hormone your pancreas produces in response to elevated blood sugar levels after eating. When insulin resistance is left ...

There was no relevant increase in insulin degradation products observed. Up to six months at 25 °C and up to two months at 37 °C high molecular weight proteins were within specifications. Appearance, ...