Most biopsies of patients with eczema did show "sparse keratinocyte necrosis." Whether this will become a histologic marker for calcium channel blocker-related eczema remains to be seen.

Misregulation of these processes can lead to several human diseases, including psoriasis and basal cell and squamous cell carcinomas. To identify novel regulators of keratinocyte differentiation, a ...

Deviation of the ambient temperature is one of the most ubiquitous stimuli that continuously affect mammals’ skin. Although the role of the warmth receptors in epidermal homeostasis (EH) was ...

Histologically, ICD lesions vary from mild keratinocyte degeneration with spongiosis to epidermal necrosis with ulceration. Typically, there are superficial changes that involve disruption of the ...

Objectives Autoimmune hepatitis (AIH) is a severe necroinflammatory liver disease associated with significant mortality. Although loss of hepatocytes is generally recognised as a key trigger of liver ...

This is true in people with a family history of the disease. What is fat necrosis? Fat necrosis is a condition where painless, round, firm lumps caused by damaged and disintegrating fatty tissues form ...

Overall, 94 keratinocyte cancers were identified in people starting a JAKi, 407 with OMA, and 628 with a TNFi.