Joost Beltman (LACDR, Leiden University) has provided novel insights in the way T-killer cells migrate towards virus-infected cells. This was accomplished by a combination of experimental research ...

Research into this link revealed that immune cells called killer T cells – responsible for destroying harmful cells and pathogens – were a key player. This new research provides insight into ...

A world-first discovery has revealed special immune cells called ‘killer T cells’ in older adults, directed against influenza viruses, closely resemble those found in newborns and children ...

The gene therapy known as CAR-T uses a patient's own T-cells to target and kill malignancies. The therapy, which has been researched for decades, is now proving effective at turning sick patients ...

T-cell receptor and have a potent immunoregulatory function. Because mouse models of allergic asthma indicate that natural killer T cells are required for the development of allergen-induced ...

CART therapy involves removing T-cells from the blood of patients and reprogramming those cells so they can recognize and destroy cancer. Novartis drummed up excitement for the technology back in ...

More information: Xin Zhou et al, CAR-redirected natural killer T cells demonstrate superior antitumor activity to CAR-T cells through multimodal CD1d-dependent mechanisms, Nature Cancer (2024 ...

Alongside antibodies, the immune system produces a battalion of T cells that can target viruses. Some of these, known as killer T cells (or CD8 + T cells), seek out and destroy cells that are ...

Cancer-specific killer T cells created from induced pluripotent stem cells (iPSC) Date: January 3, 2013 Source: RIKEN Summary: Researchers in Japan report today that they have succeeded for the ...

A new study by scientists at the Salk Institute demonstrates how “bad fats” hinder killer T cells from fighting cancer cells. Their findings are published in the journal Immunity in a paper ...

It is the first living cell therapy that can navigate through the body to a specific organ, addressing what has been a major limitation of CAR-T cancer therapies until now. The technology worked in ...

A study demonstrates that a different immunotherapy approach utilizing natural killer T cells produced significant antitumor activity in preclinical models of solid tumors. In the fight against ...