Many people have owned or known big dogs, from the gentle giant Great Danes to the sweet-tempered, bear-sized Newfoundlands.

If, after reviewing all the info on big dog breeds and fawning over pictures of huge pups, you’re convinced you want a large dog, ask yourself a few questions. The American Kennel Club’s breed ...

Mastiffs are the largest dog breed, with males weighing up to 230 pounds. Large dog breeds are frequently known for being protective. Some large breeds require more upkeep than others, making it ...

It turns out that large -- but not the largest -- dog breeds generally have the ... STOCK PHOTO/Getty Images Some of the breeds that are most prone to getting cancer are flat-coated retrievers ...

A study published Wednesday in the journal The Royal Society found that large dog breeds, but not the largest ... shows a Bernese mountain dog. (Getty Images) The file image shows a bullmastiff.