Origins of the Lisa Simpson presentation meme On March 11, 2001, The Simpsons aired an episode titled “ Bye Bye Nerdie ” in which Lisa becomes the target of a new bully in her class, Francine.

What episode is the Lisa Simpson Coffee meme from? Lisa Simpson’s coffee-loving moment comes in season 2, episode 20, “War of the Simpsons,” which aired in May 1991.