It’s more noticeable in those with enlarged Red Blood Cells (RBCs) – a condition called macrocytosis – where around 18-20% of cases are linked to low B12 levels. Additionally, people on a ...

You probably know that anemia makes you feel tired and weak, but what you might not realize is that your iron-deficient blood is forcing your heart to work overtime in ways that could permanently ...

Luspatercept shows higher efficacy than ESAs in increasing hemoglobin levels and sustaining improvement in LR-MDS patients. Patients treated with luspatercept achieve faster and more sustained red ...

Background Methotrexate is known to cause folate deficiency which can be manifested early on as macrocytosis in a complete blood count. Some clinical manifestations of folate deficiency such as ...

Mutations in the EZH2 gene are found in myelodysplastic syndrome (MDS) and are often accompanied by mutations in RUNX1. Here, the authors develop a mouse model of MDS and show that EZH2loss ...

Department of Translational and Advanced Diagnostics, Institute for Maternal and Child Health I.R.C.C.S. Burlo Garofolo, Trieste 34137, Italy ...