We have recently shown that the formation and autophagic processing of p62-enriched inclusion bodies is a critical process by which plaque macrophages mitigate atherosclerotic plaque burden 6.

In both monocytes and macrophages, changes in QKI expression ... QKI binding in the downstream intron would normally give inclusion, but now QKI cannot bind downstream; thus, exclusion is now ...

Please use one of the following formats to cite this article in your essay, paper or report: APA Mckenzie, Samuel. (2018, October 29). Macrophage to Foam Cell Differentiation Pathway. News-Medical ...

The term "macrophage" conjures images of a hungry white blood cell gobbling invading bacteria. However, macrophages do much more than that: Not only do they act as antimicrobial warriors ...

Macrophages serve as the Swiss army knives of the innate immune system, switching between phenotypes to perform different functions in response to the surrounding environment. One of their key ...

Macrophages are important cells of the immune system that are formed in response to an infection or accumulating damaged or dead cells. Macrophages are large, specialized cells that recognize ...

New methods for deriving macrophages from induced pluripotent stem cells are easier to scale and provide more clinically relevant data. Induced pluripotent stem cells (iPSCs) have given scientists ...

The results of research by scientists at Trinity College Dublin and St. Vincent’s University Hospital offer new insights into the cellular and genetic features of joint inflammation in ...

The work, published in Science in an article titled, “Macrophage peroxisomes guide alveolar regeneration and limit SARS-CoV-2 tissue sequelae,” identifies how the viral infection damages ...

Here’s a radical idea. Perivascular macrophages—those innate immune cells sitting oh-so-innocently on the small blood vessels in our brains—might be why ApoE4 carriers are more susceptible to ...