People have been celebrating the summer solstice with elaborate rituals since prehistoric times. But humans aren't the only ...

People have been celebrating the summer solstice with elaborate rituals since prehistoric times. But humans aren’t the only ...

Nicole Verdun, director of the office that reviews cell and gene therapies at the Food and Drug Administration, and her ...

Zhejiang Jingke Pharmaceuticals Co. Ltd. has identified mast/stem cell growth factor receptor kit (KIT; c-Kit; CD117) inhibitors reported to be useful for the treatment of cancer, neurodegeneration, ...

Sanofi acquires Blueprint Medicines Corporation for $9.1bn, gaining revenue-driving Aykavit and pipeline drug BLU-808 ...

For some, the word "histamine" might evoke thoughts of seasonal allergies: runny noses, scratchy throats and itchy eyes. But the molecule also ...

Shares of Jasper Therapeutics rose after the company disclosed what it called positive data from a recent trial of its treatment for chronic mast cell diseases. The stock climbed 13%, to $6.32, in ...

Some people are allergic to others – but the mystery of how this works is only just starting to be unravelled.

The therapy targets mast cells by inhibiting receptor tyrosine kinase KIT, crucial for mast cell function and survival. Significant improvements in UAS7 and quality of life were observed.

(100%) in the 180mg cohort achieved a clinical response Tryptase levels below the lower limit of quantification observed in ...